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In contrast, in some situations, particularly when combined with high-dose ACEI, DPP-4i may exhibit hypertensive effects by stimulating sympathetic activity and alleviating the degradation of GLP-1 and substance P
[245] [247] CYP2D6, dopamine -hydroxylase (DBH), flavin-containing monooxygenase 3 (FMO3), butyrate-CoA ligase (XM-ligase), and glycine N -acyltransferase (GLYAT) are the enzymes known to metabolize amphetamine or its metabolites in humans
PLoS ONE 18(8 August):120 (2016) Liraglutide and cardiovascular outcomes in type 2 diabetes
The only persistent side effect was appetite suppression, which is the intended therapeutic outcome
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