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Andrew Huberman: Great, that's very useful information, I'm sure, to a number of people out there

And with weight gain comes the return of insulin resistance. If you discontinue the medication, lifestyle interventions can partially preserve insulin sensitivity improvements after you stop taking the meds, says Silvana Obici, MD, the chief of the division of endocrinology at Stony Brook Medicine and the medical director of the Stony Brook University Hospital Diabetes Center in New York

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TRIUMPH-1: Retatrutide in Obesity (long-term safety endpoints)

Patients should be counselled about modifiable risk factors, particularly alcohol intake and weight management