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The most common causes include: Inadequate dietary intake (common in vegetarians/vegans) Malabsorption syndromes (e.g., celiac or Crohns disease) Atrophic gastritis Long-term use of acid-reducing medications Pernicious anemia (an autoimmune condition) B12 deficiency is one of the leading reversible causes of anemia
No FDA-approved KPV drug exists
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However, during the past century (especially after World War II), profound changes in dietary habits have occurred worldwide: mainly including changes from (i) meals to snacks, (ii) eating at home to eating out, (iii) eating fruits and vegetables (plant-rich diets) to eating more animal foods
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