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Published online 2022:587-592
This can make you feel tired, weak, dizzy, or even lose muscle
Many individuals with this disease meet the criteria for metabolic syndrome, especially insulin resistance and excess abdominal fat
The arrival of these drugs marks an important change in a country where many people are above a healthy weight, making them vulnerable to diseases that can take years off of their lives
For example, during the early stages of AD, deoxycholic acid accumulates in the brain and can directly impair cognition by binding with the bile acid receptor Takeda G protein-coupled receptor 5 (TGR5) on excitatory neurons, leading to STAT3 phosphorylation, Aph1 transcription, and increased A production [220]
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