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In the nucleotide-free state captured in the cryoEM structure, Ric1 wraps around the surface of Rab6 and makes extensive contacts with the switch regions of the GTPase, burying ~1350 2 surface area at the GEF domain interface (Figs

Assessing the real-world impact of sugar substitutes on weight, and the role of sweetness without calories [A: 44:00, V: 48:50]

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