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Anggayasti WL, Ogino K, Yamamoto E, Helmerhorst E, Yasuoka K, Mancera RL (2020) The acidic tail of HMGB1 regulates its secondary structure and conformational flexibility: a circular dichroism and molecular dynamics simulation study

Other possible side effects include headaches, fatigue, muscle loss, and reduced bone density

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In conclusion, research findings suggest that energy metabolism abnormalities may be the cause of the vulnerability of dopaminergic neurons in the substantia nigra of PD patients