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Mutation accumulation in the intestine and colon of mice deficient in two intracellular glutathione peroxidases
In addition, GHK-Cu influences cellular proliferation, migration, and differentiation, supporting angiogenesis and stem cell function, ultimately promoting tissue repair and remodeling in diverse tissues including skin, bone, and lung 1-4
Consistent with the notion that this axis directly promotes histone acetylation, supplementation with acetylcarnitine, but not l-carnitine, rescued histone acetylation in cells with knockdown of CrAT (Extended Data Fig
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