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Together they dwarfed the next-closest drug class (ADHD)

[3] Busetto et al

doi: 10.1210/jcem.80.3.7883856 99 KiefferTJMcIntoshCHPedersonRA

If your Aetna plan requires step therapy, your healthcare provider may need to document that you tried and failed to use a lower-cost alternative such as metformin and it didnt work for you

Understanding when lifestyle interventions alone are insufficient is essential for appropriate patient care and preventing disease progression