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Semaglutide reduces hunger signals from the brain, making it easier for patients to feel satisfied with smaller meals

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This can put you into a starvation-like state that your body responds to by increasing your hunger and appetite, as well as your fat production. What does semaglutide do to your body

Look AHEAD post hoc analyses showed that body weight reductions of 10% or increasing fitness by two metabolic equivalents in the first year was associated with an approximate 20% reduction in risk of cardiovascular disease, compared to no associations observed with small or moderate weight loss [18]

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