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DSIP in humans can thus sustain natural sleep functions, and is well tolerated, with no obvious side effects observed
To further evaluate T-cell metabolic transcriptional programs in an independent cohort, we analyzed GSE189536, a kidney allograft biopsy single-cell/CITE-seq dataset containing transcriptomic libraries from 5 TCMR and 3 non-rejection biopsies
Furthermore, increased copper levels can increase reactive oxygen species (ROS) production and activate the NF-B signalling pathway, exacerbating inflammatory changes within the vascular wall and promoting atherosclerosis (25)
*Correspondence: Yu Zhou, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
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