Gozes group has found that ADNP mutations affect MT dynamics and inhibit its interactions with Tau [348, 349], producing a tauopathy-like phenotype manifested in increased GSK-3 activity, Tau hyper-phosphorylation, and cognitive deficiency [293]
Studies suggest that by the 60s, glutathione may be reduced by up to 50% compared with younger levels [15]
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Efficacy and safety of electroacupuncture for metabolic dysfunction-associated fatty liver disease: a study protocol for a multicentre, randomised, sham acupuncture-controlled, patient-blinded clinical trial
As a result, the aberrant protein SNO may significantly affect neuronal functions, thereby contributing to behavioral deficits in ASD