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2009 Jan 27;106(4):1285-90
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Fetuses have essentially no meaningful Phase II detox capacity in the first trimester, and adolescents face a second sensitive window during hormonal reprogramming at puberty
It alters the enzymatic environment through which many other drugs pass, and researchers combining it with tirzepatide while also taking additional medications need to review their complete medication list for CYP450 interactions
doi: 10.3390/nu17132145 92
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