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It is important to note that DSIP remains largely investigational, and formal clinical guidelines for its use have not yet been established

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The main message is that GLP-1 therapy behaves more like a long-term risk-reduction treatment than a short-term fix, said Robert Glatter, MD, attending physician in the Department of Emergency Medicine at Lenox Hill Hospital in New York City, and assistant professor of Emergency Medicine at Zucker School of Medicine at Hofstra/ Northwell, in a previous interview

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Some researchers find ginger supplements or antiemetic medications helpful during the first few weeks at this tier

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Patients continue to manage their appetite, focusing on healthy eating habits

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The FDA prescribing information for GLP-1 receptor agonists, including semaglutide, notes an increased risk of acute gallbladder disease (cholelithiasis, cholecystitis), which can present with jaundice and elevated liver enzymes that might be mistaken for direct liver injury

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