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The two figures are not a like-for-like pair, and the common gloss that the 2.3-point gap is the adherence penalty does not survive inspection
Presented for research literature review only Hrelec M et al
Phase 2 trial (Lancet 2021) tested cagrilintide 0.3 mg through 4.5 mg/week as monotherapy and reported a clear dose-response, with 10.8% mean weight loss at 4.5 mg/week at 26 weeks
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