PT-141 (alternatively, bremelanotide) is a synthetic cyclic heptapeptide that emulates the function of -melanocyte stimulating hormone (alpha-MSH), a hormone mainly secreted by the pituitary gland [1]
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For instance, a single dose of semaglutide or exenatide reduced circulating levels of tumor necrosis factor (TNF-) in mice challenged with lipopolysaccharide (LPS)
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Wang, X., Chen, J., Rong, C., Pan, F., Zhao, X., & Hu, Y