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In experimental protocols it is administered daily during the loading phase, then twice weekly maintenance
Five children with neither supplementation nor a known chronic illness were later diagnosed with a malignancy, including chronic myeloid leukemia
Furthermore, combining BPTES with chemotherapeutic drugs resensitizes drug-resistant cancer cell lines to chemotherapy, regardless of their glutamine dependence status (Masamha and LaFontaine, 2018)
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