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Our incredibly smart and talented intern, Julia Pougnet-Green, took on a 12-week development project for us

Investigation, LH and DF

REDEFINE 1 Combination Data The closest analog for layered amylin + incretin tolerability is REDEFINE 1, where cagrilintide 2.4 mg was paired with semaglutide 2.4 mg: The pattern: layering cagrilintide on a GLP-1 backbone produced modestly more GI events than the GLP-1 alone, but discontinuation rates were similar

Most involve a relatively small number of subjects, and few of the research teams seem to have actually published papers describing their methods and data

You will also learn the science behind degradation, so you understand not just what to do but why each step matters