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It also helps to deplete the lactic acid in your muscle cells while you train, resulting in less discomfort when increasing weights and allowing you to continue training with increased intensity with less pain

Vanhove et al., 2019)

Metabolic research models, Cardiovascular Disease, and the Promising Role of [PMID: 37640171] Laboratory literature summary: metabolic research models, Cardiovascular Disease, and the Promising Role of Semaglutide: Insights from the SELECT Trial

210,211 The weight loss effects from GLP-1 RA treatment may reverse these changes and alter the pharmacokinetics of co-administered lipophilic drugs by decreasing the Vd (Figure 3)

But the American Society of Anesthesiologists (ASA) urges caution: "The potential benefit of withholding GLP-1s around surgery must be balanced against the risks." Why