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In a key secondary endpoint, from a baseline weight of 207 lb., Mounjaro reduced participants' weight by a mean of 17 lb

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Morning total testosterone below 300 ng/dL should be confirmed with a second measurement, and additional testing (LH, prolactin) may be warranted if low testosterone is confirmed

Patients with pre-existing gastrointestinal conditions, including GERD, peptic ulcer disease, or gastroparesis, should have closer monitoring during GLP-1 initiation and dose escalation