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There was limited density for the conjugated lipid, which could only be resolved in high-resolution receptor-focused maps of Cagri-AMY 1 R-G s and Cagri-CTR-G s structures, albeit modelling was restricted to the Glu linker and an adjacent short segment of the fatty diacid as the remainder of the modification was not resolved
IGFR can directly activate C (PLC), followed by phospholipid hydrolysis to produce diacylglycerol, or DAG, and inositol-4,4,4-triphosphate, or IP3 [43]
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Blood 104:274b, 2004
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