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In addition, polymeric nanovesicles Gem/Sul-NP which simultaneously encapsulate and deliver gemcitabine and the prolyl isomerase Pin1 inhibitor sulfopin, can effectively remodel the immunosuppressive TME and significantly increases the infiltration of CD8 IFN T cells when combined with anti-PD-1 therapy (190)

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[Abstract] mBio

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Archived from the original on January 10, 2012