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It has also been noted that MMNSTs typically grow along a spinal nerve root with a unique dumbbell configuration, though this is a nonspecific finding, as many types of tumors assume this configuration if they contain intradural and extradural components
However, under this condition, placental growth hormone may take this role as the prime regulator of maternal serum IGF-I during pregnancy[189], being of particular interest the positive expression of IGF-IR in placenta[190] and the lower expression of placental-derived IGF-I during IUGR[191]
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