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Description

W.et al (2009)

It just hasn't been rigorously tested in humans

Using a human intestinal epithelial platform with functional L-cells, researchers can now directly stimulate the epithelium and measure endogenous GLP-1 and other incretin secretion in a physiologically relevant context enabling mechanistic interrogation of secretion biology upstream of receptors

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Unlike many traditional approaches that focus on blood flow or hormone levels, PT-141 works through the central nervous system, targeting pathways in the brain involved in desire and arousal