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Most healthy adults have a heavy store (up to several years worth) of B12 in their liver

However, some patients experience nausea, especially during dose increases, which usually resolves within days to weeks

In some cases, over-the-counter laxatives may be suggested for short-term relief, but it is crucial for patients to discuss these options with their healthcare team to ensure they are safe and appropriate for their specific situation

The glutamate transport inhibitor dl-Threo--benzyloxyaspartic acid (DL-TBOA) differentially affects SN38- and oxaliplatin-induced death of drug-resistant colorectal cancer cells

This ingredient is also referred to as pro-vitamin B5