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Higher doses increase gastrointestinal side effects without proportional benefits
Furthermore, Tirzepatide, administered once weekly at 15 mg, proved to be more effective than Semaglutide, administered once weekly at 1 mg, in reducing HbA1c levels
Presented for research literature review only al-Ghais SM et al
Its oral drug o rforglipron , currently in phase 3 trials for obesity and T2D, is a daily oral GLP-1 that could appeal to patients that prefer not to inject themselves, as well as for patients that are located in geographies that lack the necessary cold chain infrastructure to adequately transport and store the injectables
Tirzepatide has already gained recognition for its effectiveness in managing weight and blood sugar, while Mazdutide, a newcomer still in clinical trials , is starting to make headlines
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