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Glucagon is secreted from pancreatic -cells and through activation of the glucagon receptor (GCGR), stimulates glycogenolysis and lipolysis

A 5% weight reduction is believed to have a clinically meaningful effect on metabolic health

This protein-stabilizing action has been demonstrated across various riboflavin-responsive metabolic disorders, highlighting its dual role in both metabolic support and proteostasis maintenance

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The study has several important caveats