Data availability Details of the search strategy and list of identified articles can be found at Abbreviations BGM: Blood glucose monitoring CGM: Continuous glucose monitoring CSII: Continuous subcutaneous insulin infusion CVOT: Cardiovascular outcomes trial DKA: Diabetic ketoacidosis DPP-4i: Dipeptidyl peptidase-4 inhibitors DSMES: Diabetes self-management education and support ETD: Estimated treatment difference GIP: Glucose-dependent insulinotropic polypeptide GLP-1 RA: Glucagon-like peptide-1 receptor agonist(s) HF: Heart failure HHF: Hospitalisation for heart failure MACE: Major adverse cardiovascular events MNT: Medical nutrition therapy NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis SGLT1i: Sodiumglucose cotransporter-1 inhibitor SGLT2i: Sodiumglucose cotransporter-2 inhibitor(s) TZD: Thiazolidinedione UACR: Urinary albumin/creatinine ratio References Rodriguez-Gutierrez R, Gionfriddo MR, Ospina NS et al (2016) Shared decision making in endocrinology: present and future directions

First isolated from human plasma albumin by Loren Pickart in 1973, GHK-Cu has been studied for its roles in wound healing, tissue remodeling, anti-inflammatory effects, and gene expression modulation
The in vitro reduction in viscosity of human tracheobronchial secretions by acetylcysteine
Protein Distribution : Aim for 20-30g of protein at each meal to support muscle preservation during weight loss
Injection site reactions are also relatively common and may include redness, itching, swelling, or mild pain at the injection site