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Maternal age was obtained by the question How old was participants biological mother when s/he was born [23]? BMI at or above the 85th and below the 95th sex-specific percentile of the BMI-for-age growth chart was defined as overweight according to the CDC [24]

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In the current study, depriving RPE cells of the essential GSH precursor Cys 2 by culturing cells in Cys 2 -free culture medium or blocking de novo synthesis of GSH by using GCL inhibitor BSO or blocking Cys 2 uptake by pharmaceutical inhibition of system x c caused cell death