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Weight cycling, when someone goes back and forth between losing weight and regaining it, occurs when the body, brain, and even the diet itself work against sustainable weight loss: The body: Biologically, the body may slow metabolism and reduce total energy expenditure in response to fewer calories

Particularly, intracellular pH can be elevated to ~7.6, thus recovering bacterial growth under semi-starvation to the growth with full nutrients

doi: 10.3389/fneur.2021.789784 184 FlugeMellaOBrulandORisaKDyrstadSEAlmeKet al

Heart Conditions: Caution is needed with congestive heart failure or severe heart issues

Some of these regulate pancreatic hormones such as insulin, glucagon and amylin, which can be considered as gut hormones but derived from pancreatic cells rather than intestinal lining cells