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Cell 173 , 10731081
373 These mechanistic insights are now being translated into rationally designed combination regimens in clinical trials, marking a significant shift toward biology-driven therapeutic strategies (Table 3)
Stretch marks cannot be completely prevented, but regular moisturising, hydration, and maintaining skin elasticity can help reduce their appearance
It also appears in peripheral organs and body fluids, suggesting systemic regulatory functions beyond the central nervous system
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