When GHK is coupled with copper, the peptide may quench the redox activity of copper, facilitating the non-toxic delivery of copper into the cells 46
34 These effects are achieved by the expression and translocation of apical glucose transporter type 4 (GLUT4) thus increasing glucose uptake and by the inhibition of pro-apoptotic proteins such as Bad, Bax and FOXO family proteins, thereby improving beta cell survival
4 x 279 .
Months 1-2: Weight Loss Accelerates What the trials documented: In the Phase 2 monotherapy trial, weight loss accrued steadily through the dosing period, building toward the 26-week endpoints of 9.1% at the 2.4 mg dose and 10.8% at 4.5 mg (Lau et al., 2021)
the method of the present invention is simple to operate, high in reaction rate, and low in cost, and is suitable for scale production with high purity and yield