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However, their potential in drug delivery and industrial applications quickly became apparent

The total hydrophilic score of most SlUGT genes was negative, only three UGT genes ( SlUGT29 , SlUGT35 , and SlUGT51 ) were positive in hydrophilicity, indicating that most SlUGT genes were hydrophilic (Supplementary Table S1)

Roles of Nicotinamide N-Methyltransferase in Obesity and Type 2 Diabetes (review)

p-value: 0.016 and 0.025)

It can result from elevated estrogen production (excess adipose aromatase activity), reduced estrogen clearance (impaired hepatic Phase I or Phase II metabolism), low SHBG (leaving more biologically active free estrogen), xenoestrogen exposure, or progesterone insufficiency