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The liver then oxidizes this TMA into Trimethylamine N-oxide (TMAO), a metabolite strongly associated with an increased long-term risk of atherosclerosis and cardiovascular disease
Patients taking tirzepatide should maintain open communication with their healthcare team and know when to seek medical advice
However, its high cost and limited accessibility remain major challenges, particularly for low- and middle-income countries
10.1038/nrm3311 29 HarhayG
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