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The most common side effects are gastrointestinal, such as nausea, diarrhea, vomiting, and constipation
These lifestyle interventions work synergistically with laxatives when needed and support long-term bowel health throughout GLP-1 treatment
Glucagon receptor activation increases hepatic glucose output and, at doses balanced against GLP-1R-mediated insulin secretion, raises basal metabolic rate by 10 to 20% in preclinical models without net hyperglycemia
They help reduce body weight by reducing hunger, slowing digestion, boosting metabolism, and improving fat breakdown (lipolysis) while preserving muscle mass
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