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This mechanism was also confirmed in subsequent studies

The pepper gene CaBPR1 , which encodes basic PR1, was strongly induced by ethephon, wounding, and virus infection

Titration intervals shorter than 7 days do not allow sufficient time for steady-state plasma levels to establish or for delayed responses to manifest, leading to premature dose escalation and increased risk of side effects

A lyophilized vial in the same conditions will be fine because the degradation reactions that heat accelerates require water to proceed