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However, a retrospective study by Richardson et al

doi: 10.1900/RDS.2014.11.202 46 HabeggerKMHeppnerKMGearyNBartnessTJDiMarchiRTschopMH

This is a critical issue, as a decrease in muscle mass leads to a reduction in basal metabolic rate [41, 42], which could hinder the long-term benefits of obesity treatment by impairing the overall metabolic profile

Here is the logic

Its important to recognize that abruptly stopping GLP-1 therapy can lead to common challenges, including weight regain and anxiety about ending treatment