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In vivo, Ex-4 has been demonstrated to inhibit prostate cancer cell growth by activating GLP-1R, reducing s-phase kinase-associated protein-2 (SKP2) gene expression, subsequently increasing p27Kip1 (p27) protein levels, and inducing tumor cell cycle arrest [67]
The authors referenced studies comparing the amount of GLP-1 produced after a solid high protein meal versus a liquid one
Glucose variability based on continuous glucose monitoring assessment is associated with postoperative complications after cardiovascular surgery
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