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The D-amino acid substitution preserves the spatial orientation of amino acid side chains needed for competitive binding to the FOXO4-p53 interaction surface, maintaining biological activity despite the non-natural backbone (PMID: 28340339)
See how your lifestyle is actually changing your bodyfat, muscle, and health markerswith a BodySpec DEXA scan
J Natl Cancer Inst (2009) 101(7):50718
Our talk on odds ratios is important, but so is how coffee affects treatment
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