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While this risk has not been confirmed in human epidemiological studies, patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use orforglipron or any GLP-1 receptor agonist
JAMA (2018) 320(15):15609
In reality, losing some muscle mass can happen with any form of weight loss
D.QuerciF.et al (2010b)
Effects of diabetes mellitus on sperm quality and fertility outcomes: Clinical evidence
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