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Medical History The presence of comorbidities such as type 2 diabetes, hypertension, hormonal imbalances or dyslipidemia may influence weight loss results

SMS SMS encodes spermine synthase (SMS) and catalyzes the conversion of spermidine (SPD), a naturally occurring polyamine, to spermine

The included studies showed notable geographical diversity, with the majority originating from Europe and Asia

Histopathological analysis revealed significant monocyte infiltration and fibrosis in the lacrimal glands of these mice, illustrating the link between mitochondrial oxidative damage and lacrimal gland dysfunction in DE [48, 49]

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