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The answer is short and simple: We dont know
A systematic review and meta-analysis synthesizing evidence from CVOTs with a total of 56,004 participants did not identify an increased risk of HF in such patients (reducing all-cause mortality by 12% and hospital admission for HF by 9%) [60]
Some patients may need dose adjustment at a faster pace than others, and other patients may need to slow down how quickly they increase the dose of the medication
Published case literature has associated Melanotan II with concerning events including new or changing melanocytic nevi and reported melanoma, priapism, rhabdomyolysis, and renal infarction
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