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Common symptoms include (x): Urgent need to urinate that is not related to how much liquid a person drank or any other obvious reason Frequent need to urinate which, like urgency, cant be explained by other factors Pain, discomfort, pressure and/or tenderness in the bladder or pelvic area sometimes pain occurs as the bladder begins to fill and subsides after being emptied Causes of Interstitial Cystitis Currently, the exact cause of interstitial cystitis is unknown

Preparation and route: Injectable versus oral forms differ in bioavailability and stability

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1a) 52,57,58,59 , and truncation of a single C-terminal amino acid residue (L585) weakens FcRn binding affinity and, consequently, reduces its in vivo plasma half-life 60,65