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Anecdotal patient reports present a mixed picture
Participants received tirzepatide or placebo for 72 weeks (Jastreboff et al., NEJM 2022)
PMID: 24678906
To identify the cause of hyponatremia, it is essential to assess the patient's volume status, clinical history, concomitant medications, and serum levels of potassium, glucose, creatinine, blood urea nitrogen, and bicarbonate
They are all class B1 GPCRs, share significant sequence similarity (Usdin et al., 1993) and form secretin-VIP receptor family ( GIPR Expression The human GIP receptor (GIPR) gene is 13.8 kb long containing 14 exons
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