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Severe or persistent symptoms should be discussed with a clinician, especially if dehydration occurs
Pathogenic and non-pathogenic
Body weight loss was observed after 10 weeks of oral semaglutide treatment in the multiple-dose trial in both healthy subjects (mean baseline body weight approximately 84 kg) and subjects with T2D (mean baseline body weight approximately 95 kg)
Demand for these medications, known as GLP-1s, has skyrocketed, but with that demand has come a shadow market: unregulated, compounded versions of GLP-1 drugs being sold online, often with misleading claims about safety and approval
The pooled estimates may be underestimates of the efficacy of newer agents, although the review could not determine whether stronger weight-loss effects necessarily translate into greater reductions in binge eating
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