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Supporting a dominant role for diet composition in establishing the Firmicutes : Bacteroidetes ratio, previous work has shown that mice maintained on a high-fat diet had a similar cecal Firmicutes : Bacteroidetes ratio to those maintained on a high-carbohydrate diet 77

Even a slight miscalculation can affect results or cause unwanted side effects

These findings align with previous research demonstrating the therapeutic potential of natural products like Cinnamaldehyde, Sarsasapogenin-AA13, Ginkgo biloba extracts, and active components of Andrographis paniculata in targeting these pathways for AD treatment [49, 89,90,91,92]

These animals were also subjected to the same environmental conditions and treatment protocols for a chronic 28-day administration study [2]

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