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Nu este recomandat pentru copii, femei nsrcinate i care alpteaz
It helps protect the DNA
Less ideal candidates Serious acute injuries requiring maximum healing support probably need injectable protocols
Concretely, GPX4 uses GSH as the substrate to reduce phospholipid hydroperoxides (PLOOHs) to hydroxyl derivatives (PLOHs), and oxidizes GSH to GSSH, therefore alleviating the damage of oxidative stress to tumor cells ( As a case in point, Li and co-workers loaded dihydroartemisinin (DHA) into iron-based MOFs to design a peroxidase-like nanoreactor (termed DHA@MIL-101 NR) for synergistic CDT-ferroptotic therapy (Figure 5C) (Yang et al., 2022a)
Combination strategies with ADCs have shown considerable promise as emerging therapies in further investigations and clinical trials [211]
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