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103,104,105 The bioactive form of vitamin D (1,25(OH)2D3) also promotes the translocation of -catenin from the nucleus to the plasma membrane, represses -catenin-TCF-4 transcriptional activity, and finally activates the transcription of the DICKKOPF-1 gene, which encodes an extracellular Wnt inhibitor

When DEGs were cross-referenced to a metabolic gene list (2,921 genes) compiled from previously published studies 6,32 , we observed significant overrepresentation of metabolic DEGs, as determined by Fishers exact test (Extended Data Fig

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