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They work by drawing water into the intestines from surrounding tissues, which softens the stool and helps it move through the intestines more easily
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Unlike semaglutide, which targets only GLP-1 receptors, tirzepatide is a dual agonist that activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
There is no official link between microdosing and improved tolerability profiles, as this dosing strategy has not been subjected to controlled clinical trials
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and GLP-1/GIP dual agonists, collectively referred to as GLP-1-based medications, have transformed the treatment landscape for obesity and cardiometabolic disease
