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To overcome this, treatment with REO significantly restored these parameters by improving antioxidant status and decreasing lipid peroxidation

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Changes in body composition, skin elasticity, and lean muscle mass generally require three to six months of consistent daily adherence to become clinically evident

Yet, we have also seen that a physiological decrease occurs with advancing age

Clinical data insights: In a large placebo-controlled trial, tesamorelin raised IGF-1 by 181% on average, but about 5% of participants discontinued due to adverse events, most commonly musculoskeletal pain and injection-site irritation (Falutz et al., NEJM )