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The trade-offs to weigh: compounded products lack the FDA finished-product approval, supply consistency depends on the pharmacy, and the boxed warning for thyroid C-cell tumors that applies to branded semaglutide and tirzepatide based on rodent studies applies to the compounded versions as well

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She said a combined approach with endoscopic sleeve gastroplasty could lead to an average weight loss of about 28% to 30% of total body weight, and with bariatric surgery, it could be from 25% to 40%